Professor David Grayden is Deputy Head (Academic) of the Department of Electrical and Electronic Engineering and Leader of the Bionics Laboratory in the Centre for Neural Engineering, The University of Melbourne. Prof Grayden's main research interests are in understanding how the brain processes information, how best to present information to the brain using medical bionics, such as the bionic eye and bionic ear, and how to record information from the brain, such as for brain-machine interfaces. 

He is also conducting research in epileptic seizure prediction and electrical stimulation to prevent or stop epileptic seizures. He has research linkages in Australia with Cochlear Limited, the Bionics Institute, St Vincent's Hospital Melbourne, Royal Melbourne Hospital, NICTA, University of South Australia, Florey Institute for Neuroscience and Mental Health.

Prof Grayden teaches in the Bioengineering and Biomedical Engineering programs in the Melbourne School of Engineering.  He teaches BioDesign Innovation, Neural Information Processing, and Biosystems Design. He also contributes to the Neuroscience Research Training course modules.