Professor Ogston has been interested in various aspects of the application of physicochemical ideas and methods in the field of biochemistry and physiology. These include: (1) assessment of the constitution, configuration and physiological functions of hyaluronic acid; (2) theory and applications of physical methods to the determination of the characteristics of macromolecular particles in solution; (3) theoretical and critical papers on a variety of topics including enzyme kinetics and specificity, protein structure and the thermodynamics of metabolic processes. His present research interests are mainly in category (1).