Belinda Medlyn is a plant physiological ecologist and mathematical modeller known for her ground-breaking contributions to understanding and predicting plant responses to climate change. Bridging the traditional divide between experimental ecology and modelling with innovative quantitative syntheses, her work has provided a compelling basis for long-term prediction of plant responses to rising CO2 concentrations, warming temperatures, and drought. Her work has been integrated into the mathematical models used to predict Earth system dynamics worldwide.