Georgia Chenevix-Trench is a cancer geneticist, internationally recognised for her work on the genetics of breast, ovarian and other cancers. She played a critical role in the identification of the PTCH gene, responsible for nevoid basal cell carcinoma syndrome. Georgia has also led ground breaking work that showed that mutations in the ATM gene confer moderate risks for breast cancer, which has major implications for research in the genetic architecture of other complex diseases. She leads an international consortium focused on identifying genetic modifiers of the breast cancer genes, BRCA1 and BRCA2, which will enable personalised risk prediction in mutation carriers.