Professor Susan Clark has a highly acclaimed international reputation for her work in human cancer epigenetics. She is best known for the development of DNA methylation and histone modification sequencing technologies to investigate complex relationships between epigenetic alterations and gene control in normal and cancer cells. Her recent research has revolutionised the field of epigenetics through pivotal discoveries of the spatial and temporal epigenetic mechanisms that underpin cancer and other diseases. Susan has also led the translation of this knowledge into the clinical setting to improve cancer outcomes.