Professor

John Miners

FAA FAHMS

John Miners
Image Description
Miners has made seminal contributions to the characterisation of the enzymatic basis of drug metabolism, which underlies the individualisation of drug therapy in humans. His research has interwoven molecular, biochemical and clinical approaches to identify sources of variability in drug metabolism, characterise the substrate and inhibitor selectivities and structure-function relationships of the key drug metabolizing enzymes cytochrome P450 and UDP-glucuronosyltransferase, and develop in vitro experimental paradigms that predict drug metabolism parameters in humans. The research has played a pivotal role in establishing drug metabolism as a predictive science that underpins both preclinical drug development and the clinical use of drugs.

Fields of research

32 BIOMEDICAL AND CLINICAL SCIENCES
  • 3214 PHARMACOLOGY AND PHARMACEUTICAL SCIENCES
    • 321401 Basic Pharmacology
    • 321402 Clinical Pharmacology and Therapeutics
    • 321406 Pharmacogenomics
    • 321499 Pharmacology and Pharmaceutical Sciences not elsewhere classified

For full list of research codes, please visit the ARC Website .

Expertise type

  • Cancer Therapy
  • Drug Discovery
  • Drug Mechanisms
  • Protein Structure-Function Relationships
  • Enzymology
  • Medical Sciences
  • Pharmacokinetics
  • Pharmacology

Please contact fellowship@science.org.au to request any updates to the data.